Sam is locked in Bobby’s panic room to cleanse his body from demon blood. However, after several seals are broken Bobby wants to set Sam free to help stop the Apocalypse and Dean seeks out Castiel for help.
Dean has a dream about Castiel asking to meet him in private. Sam and Dean are shocked to discover Castiel’s human host, Jimmy, is back in control. Jimmy wants his life back but Sam and Dean believe he is in danger.
Sam and Dean are on a hunting trip when they receive a call from an Adam Milligan, who is trying to find John Winchester. They discover that Adam was conceived 19 years ago when his mother fell in love with John Winchester.
Sam and Dean come across a series of novels called Supernatural depicting their lives as demon hunters in detail. The brothers meet the author of the comics, Chuck, who explains he has visions of Sam and Dean in action then puts their adventures in his novels.
Dean and Sam now lead ordinary lives. Dean works in the corporate world at the Sandover Bridge & Iron Company along with Sam who works as a Tech Support. Both have no idea who the other is until their colleagues start killing themselves.